Jay M. Goldberg (1935 – 2019) was a physiologist at the University of Chicago who published pioneering, basic-science research on vestibular neurophysiology (Baird et al. 1988; Boyle et al. 1992; Brichta et al. 2002; Brichta and Goldberg 1996, 1998, 2000a, b; Chen-Huang et al. 1997; Demer et al. 1987; Demer et al. 1990; Demer et al. 1989; Fernández et al. 1988; Fernandez and Goldberg 1976a, b, c; Fernandez et al. 1972; Fernández et al. 1990; Fernández et al. 1995; Goldberg 1991, 1996a, b, 2000; Goldberg and Brichta 1998; Goldberg and Cullen 2011; Goldberg et al. 1990a, b; Goldberg et al. 1987; Goldberg and Holt 2013; Goldberg et al. 1990c, 1992; Holt et al. 2006a; Holt et al. 2011; Holt et al. 2006b; Lysakowski and Goldberg 1997, 2008; Lysakowski et al. 1995; Marlinski et al. 2004; Minor and Goldberg 1990, 1991; Minor et al. 1990; Plotnik et al. 2001, 2002, 2005; Young et al. 1977).
Much of Goldberg’s research was done in collaboration with his otolaryngology colleague at the University of Chicago, César Fernández (1954 – 1999).
References
Baird RA, Desmadryl G, Fernández C, Goldberg JM (1988) The vestibular nerve of the chinchilla. II. Relation between afferent response properties and peripheral innervation patterns in the semicircular canals. J Neurophysiol 60: 182-203. doi: 10.1152/jn.1988.60.1.182
Boyle R, Goldberg JM, Highstein SM (1992) Inputs from regularly and irregularly discharging vestibular nerve afferents to secondary neurons in squirrel monkey vestibular nuclei. III. Correlation with vestibulospinal and vestibuloocular output pathways. J Neurophysiol 68: 471-84. doi: 10.1152/jn.1992.68.2.471
Brichta AM, Aubert A, Eatock RA, Goldberg JM (2002) Regional analysis of whole cell currents from hair cells of the turtle posterior crista. J Neurophysiol 88: 3259-78. doi: 10.1152/jn.00770.2001
Brichta AM, Goldberg JM (1996) Afferent and efferent responses from morphological fiber classes in the turtle posterior crista. Ann N Y Acad Sci 781: 183-95. doi: 10.1111/j.1749-6632.1996.tb15701.x
Brichta AM, Goldberg JM (1998) The papilla neglecta of turtles: a detector of head rotations with unique sensory coding properties. J Neurosci 18: 4314-24. doi: 10.1523/jneurosci.18-11-04314.1998
Brichta AM, Goldberg JM (2000a) Morphological identification of physiologically characterized afferents innervating the turtle posterior crista. J Neurophysiol 83: 1202-23. doi: 10.1152/jn.2000.83.3.1202
Brichta AM, Goldberg JM (2000b) Responses to efferent activation and excitatory response-intensity relations of turtle posterior-crista afferents. J Neurophysiol 83: 1224-42. doi: 10.1152/jn.2000.83.3.1224
Chen-Huang C, McCrea RA, Goldberg JM (1997) Contributions of regularly and irregularly discharging vestibular-nerve inputs to the discharge of central vestibular neurons in the alert squirrel monkey. Exp Brain Res 114: 405-22. doi: 10.1007/pl00005650
Demer JL, Goldberg J, Jenkins HA, Porter FI (1987) Vestibulo-ocular reflex during magnified vision: adaptation to reduce visual-vestibular conflict. Aviat Space Environ Med 58: A175-9.
Demer JL, Goldberg J, Porter FI, Jenkins HA, Schmidt K (1990) Visual-vestibular interaction with telescopic spectacles. J Vestib Res 1: 263-77.
Demer JL, Porter FI, Goldberg J, Jenkins HA, Schmidt K (1989) Adaptation to telescopic spectacles: vestibulo-ocular reflex plasticity. Invest Ophthalmol Vis Sci 30: 159-70.
Fernández C, Baird RA, Goldberg JM (1988) The vestibular nerve of the chinchilla. I. Peripheral innervation patterns in the horizontal and superior semicircular canals. J Neurophysiol 60: 167-81. doi: 10.1152/jn.1988.60.1.167
Fernandez C, Goldberg JM (1976a) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. I. Response to static tilts and to long-duration centrifugal force. J Neurophysiol 39: 970-84. doi: 10.1152/jn.1976.39.5.970
Fernandez C, Goldberg JM (1976b) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. II. Directional selectivity and force-response relations. J Neurophysiol 39: 985-95. doi: 10.1152/jn.1976.39.5.985
Fernandez C, Goldberg JM (1976c) Physiology of peripheral neurons innervating otolith organs of the squirrel monkey. III. Response dynamics. J Neurophysiol 39: 996-1008. doi: 10.1152/jn.1976.39.5.996
Fernandez C, Goldberg JM, Abend WK (1972) Response to static tilts of peripheral neurons innervating otolith organs of the squirrel monkey. J Neurophysiol 35: 978-87. doi: 10.1152/jn.1972.35.6.978
Fernández C, Goldberg JM, Baird RA (1990) The vestibular nerve of the chinchilla. III. Peripheral innervation patterns in the utricular macula. J Neurophysiol 63: 767-80. doi: 10.1152/jn.1990.63.4.767
Fernández C, Lysakowski A, Goldberg JM (1995) Hair-cell counts and afferent innervation patterns in the cristae ampullares of the squirrel monkey with a comparison to the chinchilla. J Neurophysiol 73: 1253-69. doi: 10.1152/jn.1995.73.3.1253
Goldberg JM (1991) The vestibular end organs: morphological and physiological diversity of afferents. Curr Opin Neurobiol 1: 229-35. doi: 10.1016/0959-4388(91)90083-j
Goldberg JM (1996a) Theoretical analysis of intercellular communication between the vestibular type I hair cell and its calyx ending. J Neurophysiol 76: 1942-57. doi: 10.1152/jn.1996.76.3.1942
Goldberg JM (1996b) Transmission between the type I hair cell and its calyx ending. Ann N Y Acad Sci 781: 474-88. doi: 10.1111/j.1749-6632.1996.tb15721.x
Goldberg JM (2000) Afferent diversity and the organization of central vestibular pathways. Exp Brain Res 130: 277-97. doi: 10.1007/s002210050033
Goldberg JM, Brichta AM (1998) Evolutionary trends in the organization of the vertebrate crista ampullaris. Otolaryngol Head Neck Surg 119: 165-71. doi: 10.1016/s0194-5998(98)70051-8
Goldberg JM, Cullen KE (2011) Vestibular control of the head: possible functions of the vestibulocollic reflex. Exp Brain Res 210: 331-45. doi: 10.1007/s00221-011-2611-5
Goldberg JM, Desmadryl G, Baird RA, Fernandez C (1990a) The vestibular nerve of the chinchilla. IV. Discharge properties of utricular afferents. J Neurophysiol 63: 781-90. doi: 10.1152/jn.1990.63.4.781
Goldberg JM, Desmadryl G, Baird RA, Fernandez C (1990b) The vestibular nerve of the chinchilla. V. Relation between afferent discharge properties and peripheral innervation patterns in the utricular macula. J Neurophysiol 63: 791-804. doi: 10.1152/jn.1990.63.4.791
Goldberg JM, Highstein SM, Moschovakis AK, Fernandez C (1987) Inputs from regularly and irregularly discharging vestibular nerve afferents to secondary neurons in the vestibular nuclei of the squirrel monkey. I. An electrophysiological analysis. J Neurophysiol 58: 700-18. doi: 10.1152/jn.1987.58.4.700
Goldberg JM, Holt JC (2013) Discharge regularity in the turtle posterior crista: comparisons between experiment and theory. J Neurophysiol 110: 2830-48. doi: 10.1152/jn.00195.2013
Goldberg JM, Lysakowski A, Fernández C (1990c) Morphophysiological and ultrastructural studies in the mammalian cristae ampullares. Hear Res 49: 89-102. doi: 10.1016/0378-5955(90)90097-9
Goldberg JM, Lysakowski A, Fernández C (1992) Structure and function of vestibular nerve fibers in the chinchilla and squirrel monkey. Ann N Y Acad Sci 656: 92-107. doi: 10.1111/j.1749-6632.1992.tb25202.x
Holt JC, Lysakowski A, Goldberg JM (2006a) Mechanisms of efferent-mediated responses in the turtle posterior crista. J Neurosci 26: 13180-93. doi: 10.1523/JNEUROSCI.3539-06.2006
Holt JC, Lysakowski A, Goldberg JM (2011) The Efferent Vestibular System. In: Ryugo DK, Fay RR (eds) Auditory and Vestibular Efferents. Springer New York, New York, NY, pp 135-186
Holt JC, Xue JT, Brichta AM, Goldberg JM (2006b) Transmission between type II hair cells and bouton afferents in the turtle posterior crista. J Neurophysiol 95: 428-52. doi: 10.1152/jn.00447.2005
Lysakowski A, Goldberg JM (1997) A regional ultrastructural analysis of the cellular and synaptic architecture in the chinchilla cristae ampullares. J Comp Neurol 389: 419-43. doi: 10.1002/(sici)1096-9861(19971222)389:3<419::aid-cne5>3.0.co;2-3
Lysakowski A, Goldberg JM (2008) Ultrastructural analysis of the cristae ampullares in the squirrel monkey (Saimiri sciureus). J Comp Neurol 511: 47-64. doi: 10.1002/cne.21827
Lysakowski A, Minor LB, Fernández C, Goldberg JM (1995) Physiological identification of morphologically distinct afferent classes innervating the cristae ampullares of the squirrel monkey. J Neurophysiol 73: 1270-81. doi: 10.1152/jn.1995.73.3.1270
Marlinski V, Plotnik M, Goldberg JM (2004) Efferent actions in the chinchilla vestibular labyrinth. J Assoc Res Otolaryngol 5: 126-43. doi: 10.1007/s10162-003-4029-7
Minor LB, Goldberg JM (1990) Influence of static head position on the horizontal nystagmus evoked by caloric, rotational and optokinetic stimulation in the squirrel monkey. Exp Brain Res 82: 1-13. doi: 10.1007/bf00230832
Minor LB, Goldberg JM (1991) Vestibular-nerve inputs to the vestibulo-ocular reflex: a functional-ablation study in the squirrel monkey. J Neurosci 11: 1636-48. doi: 10.1523/jneurosci.11-06-01636.1991
Minor LB, McCrea RA, Goldberg JM (1990) Dual projections of secondary vestibular axons in the medial longitudinal fasciculus to extraocular motor nuclei and the spinal cord of the squirrel monkey. Exp Brain Res 83: 9-21. doi: 10.1007/bf00232188
Plotnik M, Marlinski V, Goldberg JM (2001) Efferent-mediated binaural interactions between the vestibular end-organs in the chinchilla. Ann N Y Acad Sci 942: 479-81. doi: 10.1111/j.1749-6632.2001.tb03774.x
Plotnik M, Marlinski V, Goldberg JM (2002) Reflections of efferent activity in rotational responses of chinchilla vestibular afferents. J Neurophysiol 88: 1234-44. doi: 10.1152/jn.2002.88.3.1234
Plotnik M, Marlinski V, Goldberg JM (2005) Efferent-mediated fluctuations in vestibular nerve discharge: a novel, positive-feedback mechanism of efferent control. J Assoc Res Otolaryngol 6: 311-23. doi: 10.1007/s10162-005-0010-y
Young ED, Fernandez C, Goldberg JM (1977) Responses of squirrel monkey vestibular neurons to audio-frequency sound and head vibration. Acta Otolaryngol 84: 352-60.
